subcutaneous necrobiosis lipoidica
Histologic Features
- A thin overlying epidermis
- Multiple foci of collagen degeneration surrounded by palisaded granuloma
- Involvement of all levels of the dermis
- Scattered multinucleated giant histiocytes
- Widened septae with fibrosis and inflammatory infiltrate consisting of lymphocytes, histiocytes, and many plasma cells
- Lymphoid nodules in the deep dermis
Updated Wednesday, July 31, 2013 8:30:48 PM