spindle cell melanoma, ulcerated
Histologic Features
- An ulcerated surface
- A poorly differentiated neoplasm with large pleomorphic spindle cells arranged in poorly oriented fascicles, extending into the subcutis
- Many multinucleated giant cells with wreath-like arrangement of nuclei
- Destruction of adnexae
- Scattered inflammatory cells
- Adjacent epidermis showing a proliferation of atypical melanocytes at the basal layer
Updated Wednesday, July 31, 2013 8:30:48 PM