neuroblastoma
Histologic Features
- Sheets of monomorphous small round cells grouped into lobules by delicate fibrous tissue and vessels
- Tumoral cells with poligonal dark staining nuclei and scanty cytoplasm
- Arrangement of cells in rosettes
- A stroma rich in mats of neuropil
- Ganglionic differentiation as evidenced by enlargement of some cells with an abundant eosinophilic cytoplasm
- A positive staining with neuron specific enolase
Updated Wednesday, July 31, 2013 8:30:48 PM