malignant melanoma, superficial spreading type
Histologic Features
- A broad asymmetrical poorly circumscribed lesion
- Nests of melanocytes varrying in sizes and shapes with a tendency to confluence
- Pagetoid spread of single melanocytes and nests
- Extension of melanocytes down adnexal epithelium
- Failure of maturation with descent into the dermis
- Pleomorphism of melanocytes
- Prominent mitotic activity near the base
- Prominent solar elastosis beneath the melanocytic proliferation
- Fibroplasia of regression
- Plasma cells in numbers at the base
Updated Wednesday, July 31, 2013 8:30:48 PM