junctional dysplastic nevus with severe dysplasia
Histologic Features
- An asymmetrical proliferation of slightly atypical melanocytes, as nests and single cells at the DE junction, in association with a marked variation in sizes and shapes of the nests, ill-distribution of pigmentation and pigment incontinence, fibrosis of papillary dermis and early dropping off of melanocytes in the papillary dermis. As a whole, the lesion is asymmetrical and broad. Because of the difficulty in assessing the malignant nature of a lesion like this, we recommend removal of such a lesion in its entirety if the margins are not clear
Updated Wednesday, July 31, 2013 8:30:48 PM