giant cell tumor of tendon sheath (nodular tenosynovitis)
Histologic Features
- A well-circumscribed smooth bordered lesion located in the subcutis, composed of
- Nonfascicular spindle cells intermixed with plump oval cells
- Large numbers of osteoclast-like giant cells
- a number of scattered foamy cells
- Some giant neoplastic cells with rounded nuclei and abundant grey cytoplasm
- Extravasation of red blood cells and siderophages as well as prominent vascularity of the stroma
- Hyalinized collagen (older lesion)
Updated Wednesday, July 31, 2013 8:30:48 PM