generalized scleroderma
Histologic Features
- Hyperpigmentation of the basal layer
- Thickened sclerotic, closely packed collagen bundles
- Perivascular and interstitial infiltrate of lymphocytes, plasma cells and some eosinophils
- A decreased number of adnexal structures
- Fewer fibroblasts between collagen bundles
- Extension into the subcutis fat
Updated Wednesday, July 31, 2013 8:30:48 PM