cutaneous neuroblastoma
Histologic Features
- Sheets of monomorphous small round cells grouped into lobules by delicate fibrous tissue and vessels
- Neoplastic cells with polygonal dark staining nuclei and scanty cytoplasm
- Arrangement of cells into rosettes (Homer Wright type)
- A stroma which is rich in mats of neuropil
- Ganglionic differentiation as evidenced by enlargement of some cells with an abundant eosinophilic cytoplasm
- A positive staining with neuron specific enolase
Updated Wednesday, July 31, 2013 8:30:48 PM