Kaposi's sarcoma, nodular stage
Histologic Features
- A proliferation of small vascular spaces containing erythrocytes
- A dense proliferation of atypical spindle cells between vascular spaces forming fascicles
- Multiple unlined slits between spindle cells containing 1-2 erythrocytes
- Extravasation of erythrocytes and siderophages
- Hyalin bodies in the cytoplasm of endothelial cells
- Erythrophagia seen in some spindle cells
- Bizarre-shaped lined vascular spaces at the periphery of the nodule
- Presence of plasma cells in numbers within the lesion
Updated Wednesday, July 31, 2013 8:30:48 PM